Pre-Clinical Research Services
INNYATCRO provides critical preclinical research data and innovative solutions through the conduct of the right studies at the right time using proven experimental design, quality compliant management systems, experienced professionals, and state-of-the-art facilities with current technologies. All work has at its core scientific and operational excellence.
Chemoinformatics
Cheminformatics is the use of physical chemistry theory with computer and information science techniques, “in silico” techniques. Its application is depicted to a range of descriptive and prescriptive problems in the field of biochemistry and related molecular fields.
Drug discovery and Bioinformatics
Bioinformatic analysis can not only accelerate drug target identification and drug candidate screening and refinement but also facilitate characterization of side effects and predict drug resistance. High-through put data such as genomics, epigenetic, genome architecture, cistromic, transcriptomic, proteomic, and ribosome profiling data have all made a significant contribution to mechanism-based drug discovery and drug repurposing
In-vitro investigations
In-vitro investigations occur in a laboratory and involve studying microorganisms, human or animal cells in culture. This methodology allows the evaluation of various biological phenomena in specific cells without the distractions and potential confounding variables present in whole organisms.
Cytotoxicity studies
Cytotoxicity studies are a useful initial step in determining the potential toxicity of a test substance, including plant extracts or biologically active compounds isolated from plants. Minimal to no toxicity is essential for the successful development of a pharmaceutical or cosmetic preparation and in this regard, cellular toxicity studies play a crucial role.
Pharmacological Activities
In pharmacology, biological activity or pharmacological activity portrays the beneficial or adverse effects of a drug on living matter. When a drug is a complex chemical mixture, this activity is expended by the substance’s active ingredient or pharmacophore but can be modified by the other constituents.
Cosmetic Testing
A general definition of cosmetics references “Any substance or preparation for human use for the purpose of cleansing, beautifying or altering the appearance commonly to include personal toiletry products (such as shampoos and lotion), beauty products and fragrances. Testing and inspection of the products consist of cutting-edge clinical research studies and clinical trials for evaluation of safety, efficacy, and advertising claim support.
Cancer Biomarker Screening
Recently, the discovery of cancer biomarkers has become a major spotlight of cancer research. The widespread use of prostate-specific antigen (PSA) in the screening of prostate cancer, has stimulated researchers for identifying suitable markers to screen various other types of cancer. Biomarkers are also profitable for diagnosing, monitoring disease progression, predicting disease recurrence, and therapeutic treatment efficacy. The advent of new and improved technologies for genomic and proteomic studies like DNA and tissue microarray, two-dimensional gel electrophoresis, mass spectrometry, and protein assays along with advanced bioinformatics tools, makes biomarkers to predict outcomes during cancer management and treatment.
Sequence Analysis
In Sequence analysis, any of the DNA, RNA, or peptide sequence is subjected to a wide range of analytical methods to understand its features, function, structure, or evolution. Some of the common methodologies include sequence alignment, searches against biological databases, and other analytical methods to recognize its features, function, structure, or evolution. Methodologies used include sequence alignment, searches against biological databases, and others. With the advent of high-throughput methods for the production of gene and protein sequences, there is an exponential increase in the rate of addition of new sequences to the databases. By understanding these sequences, the biology of organisms can be gained by comparing the new sequences to those with known functions.
Phylogenetic Analysis
Phylogenetic analysis is the study of the evolutionary development of a species or a group of organisms or a particular characteristic of an organism. Phylogenetic tree is structured in phylogenetic analysis. These branching diagrams represent the evolutionary history or relationship between different species, organisms, or characteristics of an organism (genes, proteins, organs, etc.) that are developed from a common ancestor. The phylogenetic analysis provides an in-depth understanding of how species evolve through genetic changes.
Animal Experiments
Animal experiments are also known as “animal testing” that involves the procedures performed on living animals. The purposes of research into basic biology and diseases assess the effectiveness of new medicinal products, and testing the human health and/or environmental safety of consumer and industry products such as cosmetics, household cleaners, food additives, pharmaceuticals and industrial/agro-chemicals.
Thesis Design and Work
Thesis designing is a lengthy experimental, design, or theoretical report, with a problem-method-results-discussion structure. The recurrent hypothetico-deductive pattern of developing a thesis for solving a problem, constructing a methodology, and testing for results is universal in research writing. Writing and designing a thesis comprises useful material like problem statements, methodologies, and bibliographies from the thesis proposal.
Statistical Analysis
Statistical analysis is the science of collecting, exploring and presenting large amounts of data to discover underlying patterns and trends. Statistics are applied in every day research and industry for more scientific decisions to be made.